b'Scientific Session Abstracts SUNDAY APRIL 21, 202439: IS AGE CORRELATIVE WITH SURGICAL HEMODIALYSIS ACCESS MATURATION OR FUNCTIONAL PATENCY?Claire Yang, MD, Kirollos Bechay, MD, Linda Chun, MD, FACS,Wesley Lew, MD, FACS, Kaushal Patel, MD, FACSKaiser Permanente Los Angeles Medical CenterIntroduction: While there are no clear age-related guidelines on optimal initial surgical hemodialysis (HD) access, recent studies suggest that older age may be associated with decreased access maturation and patency. We look to see if within our institution there is any difference in access maturation, primary functional patency (PFP), or assisted primary functional patency (APFP) at 12 months between age groups.Methods: All adult patients with CKD or ESRD undergoing first time surgical HD access creation in either arm at our institution in 2022 were included. The 5 age groups were 50 years, 50-60 years, 60- 70 years, 70-80 years, and 80 years. Failure to mature was defined as access necessitating intervention within 3 months of creation to obtain maturity, while delayed maturation was longer than 3 months without intervention. PFP was the length of time between first successful HD access to the first intervention to maintain patency and APFP defined as time to access thrombosis including intervening interventions. Statistical analysis was performed with Kruskal- Wallis, Pearsons Chi-squared, one-way ANOVA, and two-tailed z-tests.Results: Almost all initial HD access creations were fistulas (n=62) vs grafts (n=1). More men were represented in the 70 groups (p0.01), the 50 group had fewer smokers (p=0.03), and the 60- 70 group had more smokers (p0.01). None of the other measured comorbidities or the average number of comorbidities differed between groups (p=0.11). The 50 group was more like to be on HD already at time of access creation (p=0.03), while the 60-70 group was less likely (p=0.01). There was no significant difference between groups for type of access creation (p=0.99), with 50.00-68.75% radiocephalic, 18.75-40.00% brachiocephalic, 0.00-15.00% brachiobasilic, and 0.00-12.50% graft. There was no significant difference between groups with regards to failure to mature (0.00-30.00%) or delayed maturation (12.50-31.25%) (p=0.71, p=0.77). The majority that failed to mature were radiocephalic (84.62%), but this was not found to be an independent determinant of risk of failure (p=0.11). The 60-70 and 70-80 groups had longer times to fistula maturation than the others (p=0.02). There was no significant difference across groups with regards 42 NDANNUAL MEETING|APRIL 1921, 2024|OCEANSIDE, CA 97'