b'Scientific Session Abstracts SUNDAY APRIL 21, 2024 though Mangled Extremity Severity Scores were not significantly different (3.69 vs 3.66; p=0.765). There was no difference in total blood product use over the first 24 hours between patients with and without tourniquet (16.4 vs 6.7; p=0.100), however, lower extremity injuries with tourniquets required significantly more blood products over the first 24 hours compared to lower extremity injuries without tourniquet (20.6 vs 7.1; p=0.031).Conclusions: Overall, there were no major differences in injury severity, blood product use, or limb outcomes between patients with and without tourniquet after penetrating extremity injury. Patients with lower extremity tourniquets, however, required more blood products over the 1st 24 hours compared to those without, despite similar injury severity scores. Future multicenter study will be needed to better assess efficacy of tourniquet use in limb salvage.42 NDANNUAL MEETING|APRIL 1921, 2024|OCEANSIDE, CA 111'